The number of young people living with debilitating and incurable bowel conditions worldwide is growing, but researchers now hope a one-of-a-kind microscope will help them understand such diseases and find new treatments.
According to the British Society of Gastroenterology, more than half a million people in the UK are living with inflammatory bowel disease (IBD), with Crohn’s disease and ulcerative colitis the two main forms.
While such conditions can develop at any age, experts say they are most often diagnosed between the ages of 15 and 40, blighting lives at a crucial time for education, work and relationships.
Now a new piece of kit could bring fresh hope to those affected by IBD.
“What this microscope technology and what the science we do in the lab can bring is really to understand the mechanism [of IBD] better,” said Dr Karina Pombo-Garcia, a group leader at the Rosalind Franklin Institute at the Harwell Science and Innovation Campus, Oxfordshire, where the microscope is housed.
“With IBD, and with other many diseases that we collaborate with other groups to study, there [are] some treatments, but maybe those treatments still are not maybe the best or the most targeted that we can do because we … fundamentally don’t understand the disease fully.”
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Ignorant device that at least helped me and is logical: increase martine omega-3 fatty acid intake. Increase soft vegetable intake. Reduce carbohydrate intake (bread, wheat, sugar)
The goal: reduce inflammatory load on digestive system, so it can regenerate enough to build healthy slime film.
I only learned recently that the food should not have direct contact to skin in the digestive system, but lay on slime that is produced and maintained by the mucus skin itself.
In the mucus live bacteria. The mucus serves as buffer for bacteria to survive between meals. The bacteria can eat away the mucus if not enough healthy food comes in.
It’s basically [mucus adding food (and behavior)] vs [mucus subtracting food (and behavior)].
The natural movement of the body is essential for healthy digestion. Don’t eat too late.
Bread is an issue for me, I need carbs regularly because I do not function otherwise. So no carbs during lunch is a no-go for me. Any recommendations to replace that?
Your body underwent the same evolutionary pressures as everybody else’s.
You might have reduce carbs step by step.
To be honest I don’t eat 0-carb diet because I like the taste of carbs. Keto-diet revolves around around 0-carb, you might find better info there than I can give you
Good that they got an old conventional microscope, I hope it serves them well!
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It’s a STED microscope, state of the art in 2012.
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No, it does not offer 10x resolution.
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The article is being constantly corrected for errors.
start of the art for IBD is IBEX microscopy, now 6 years old.
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